Immune-suppression
Guides
Campoletis sonorensis
Campoletis sonorensis is a parasitoid ichneumonid wasp distributed across much of the Americas, including the United States, Brazil, and Chile. It is a generalist endoparasitoid of lepidopteran larvae, with documented hosts including Spodoptera frugiperda, Spodoptera exigua, Helicoverpa species, Chrysodeixis includens, and Heliothis virescens. The species employs sophisticated immune evasion strategies involving a mutualistic polydnavirus (Campoletis sonorensis ichnovirus, CsIV) and ovarian proteins that suppress host hemocyte function and prevent encapsulation. It has been extensively studied as a model system for host-parasitoid interactions, host selection behavior, and biological control potential.