RFLP

Definition

Restriction Fragment Length Polymorphism. A technique used in molecular biology to differentiate DNA fragments based on variations in their lengths after digestion with restriction enzymes.

Etymology

From the words 'restriction', 'fragment', 'length', and 'polymorphism'.

Example

RFLP analysis can be used to identify genetic variations between individuals.

Related Terms

• Restriction enzymes
• DNA
• Polymorphism

Usage Notes

RFLP requires DNA samples and the use of restriction enzymes. The resulting fragments are then separated by gel electrophoresis.