Restriction fragment length polymorphism

Pronunciation
/re-stric-shun frag-ment length pol-ee-mor-fiz-um/
Category
Molecular Biology
Singular
Restriction fragment length polymorphism
Plural
Restriction fragment length polymorphisms

Definition

A technique used to differentiate between individuals or populations based on variations in the lengths of DNA fragments generated by restriction enzyme digestion.

Etymology

Example

Restriction fragment length polymorphism (RFLP) analysis was used to distinguish between strains of a particular insect species.

Related Terms

  • Restriction enzymes
  • DNA fingerprinting

Usage Notes

RFLP analysis requires prior knowledge of the DNA sequence being analyzed.