Stable transformation

Definition

A method of introducing foreign DNA into an organism's genome where the introduced DNA remains integrated and heritable through generations.

Etymology

From Latin 'stabilis', meaning 'stable', and 'transformation', referring to a change in form.

Example

Stable transformation is achieved using vectors that integrate into the host genome, ensuring that the introduced gene is passed down to offspring.

Related Terms

• Transgenic
• Genetically modified organism (GMO)
• Vector

Usage Notes

Stable transformation requires careful selection and optimization of vector systems and integration methods. It can be used for various purposes, including introducing disease resistance or enhancing production of valuable proteins.