RNA interference

Pronunciation
/RNA in-ter-fer-ence/
Category
Molecular Biology
Singular
RNA interference
Plural
RNA interferences

Definition

A biological process where double-stranded RNA (dsRNA) triggers the silencing of specific genes by degrading messenger RNA (mRNA) that corresponds to the target gene.

Etymology

From 'RNA' and 'interference'.

Example

The introduction of dsRNA targeting a gene involved in insecticide resistance can lead to reduced susceptibility in insect populations.

Related Terms

  • Gene silencing
  • mRNA degradation
  • Dicer
  • RISC