Exotoxins

Definition

Proteins secreted by bacteria, often exhibiting potent toxicity and specificity towards host cells.

Etymology

From Greek 'exo-', meaning 'outside', and 'toxin'.

Example

Cholera toxin is an example of an exotoxin that targets intestinal epithelial cells.

Related Terms

• Endotoxins
• Bacterial toxins
• Virulence

Usage Notes

Exotoxins are often heat-labile and can be neutralized by antibodies.